Blar i forfatter "Granslo, Hildegunn Norbakken"

Viser treff 1-4 av 4

    • Bronkiolitt skal ikke behandles med glukokortikoider eller antibiotika 

      Nordal, Ellen Berit; Granslo, Hildegunn Norbakken; Esaiassen, Eirin; Leknessund, Carina Benedikte Bjørkvoll; Forsdahl, Bård Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-30)
      Vi er inne i en hektisk sesong med virale luftveisinfeksjoner. Respiratorisk syncytialvirus (RS-virus) er den hyppigste årsaken til bronkiolitt hos barn. Pediatriveilederen er tydelig på at perorale glukokortikoider ikke har noen plass i behandlingen av bronkiolitt og at det sjelden er behov for antibiotika.

    • Metabolic responses in neonatal sepsis—A systematic review of human metabolomic studies 

      Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-13)
      Aim - To systematically review human metabolomic studies investigating metabolic responses in septic neonates.<p> <p>Methods - A systematic literature search was performed in the databases MEDLINE, EMBASE and Cochrane library up to the 1st of January 2021. We included studies that assessed neonatal sepsis and the following outcomes; (1) change in the metabolism compared to healthy neonates and/or ...

    • Staphylococcus epidermidis - virulence factors and innate immune response 

      Granslo, Hildegunn Norbakken (Doctoral thesis; Doktorgradsavhandling, 2012-04-26)
      S. epidermidis rank first among the causative agent of nosocomial infections, and accounts for more than 50% of the late-onset sepsis episodes in neonates. S. epidermidis often cause infections in immune-compromised patients Biofilm formation is the most important virulence factor of S. epidermidis. Its relevance has risen the past decades with the increased use of indwelling medical devices such ...

    • The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model 

      Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Esaiassen, Eirin; Christophersen, Lars; Jensen, Peter Østrup; Mollnes, Tom Eirik; Moser, Claus; Flægstad, Trond; Klingenberg, Claus; Cavanagh, Jorunn Pauline (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-27)
      The global spread of antimicrobial resistance and the increasing number of immune‐compromised patients are major challenges in modern medicine. Targeting bacterial virulence or the human host immune system to increase host defence are important strategies in the search for novel antimicrobial drugs. We investigated the inflammatory response of the synthetic short antimicrobial peptide LTX21 in two ...